Prior medical therapy was not mentioned at all in five studies. Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free! 2property of conductive tissue to return to original related state in preparation for a second stimulus. They may worry a lot about when their next seizure will come. The generally accepted definition of refractory seizures was proposed by Berg: failure of two or more drugs and occurrence of one or more seizures per month over 18 months (2). View the pronunciation for refractory. A refractory symptom may be subjective and, at times, nonspecific. MedicineNet does not provide medical advice, diagnosis or treatment. Conclusions: There is need for a detailed definition of pharmacologically refractory constipation before submitting patients to invasive treatments and to evaluate new pharmacological agents. refractory. © ⦠Many less attractive traits are also recorded: Charles could be uncommunicative and dilatory, evasive and mendacious, These trials routinely focus on those cancers, such as multiple myeloma and, Work is also progressing to explore bone marrow transplants as a novel pathway to treating debilitating conditions like, These fractious workplace relationships arenât so much the fault of, Another way to reduce what reaches the ground is to substitute, For instance, determining whether a heart attack needs to be urgently catheterized depends in part on if a patientâs chest pain is, Our systematic approach to research enabled the first-ever treatment (siltuximab) and discovery of a treatment for patients who are siltuximab-, Post the Definition of refractory to Facebook, Share the Definition of refractory on Twitter. Definition and synonyms of refractory from the online English dictionary from Macmillan Education. The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. Refractory: Related Topics. Advertisement The definition of refractory is stubborn or hard to manage, or heat resistant. See additional information . This is the British English definition of refractory.View American English definition of refractory. 2. not responding to a stimulus. Get Word of the Day delivered to your inbox! Refractory epilepsy can have a big effect on your life. What made you want to look up refractory? [ re-frak´tah-re] 1. not readily yielding to treatment. Refractory (uncontrolled) epilepsy is a heavy burden. The importance of defining a refractory symptom is central in utilizing palliative sedation in a safe, efficacious, and ethical manner. In 2008, the Refractory Headache Special Interest Section (RHSIS) and the American Headache Society (AHS) set out to define criteriafor refractory chronic migraine. 2 The first study involved 30 patients with refractory gastroparesis. If your doctor thinks you have refractory epilepsy, he or she may suggest that you visit a medical center that specializes in epilepsy. Refractory: In medicine, describes a disease or condition that does not respond to treatment. In some cases, refractory migraine is used synonymously with chronic migraine, or referred to as intractable migraine. believing that rules are only for other people, he's been, One advancement has come in the ability to manufacture. Refractory in Community Dictionary what's a place where you could check-out get fractORRZZED. If you've been treated for depression but your symptoms haven't improved, you may have treatment-resistant depression. ry. The meaning of refractory cancer is cancer that fails to respond to medical treatment. Showing or characterized by obstinate resistance to authority or control: refractory children; refractory behavior. Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment. A refractory symptom is one that cannot be adequately controlled despite aggressive efforts to identify a tolerable therapy that does not compromise consciousness (Cherny 1994). 3. difficult to fuse, reduce, or work, as an ore or metal. Then, intractable, the one works best is highlighted in yellow – difficult to alleviate, remedy or cure: intractable pain. (rÄ-frÄkâ²tÉ-rÄ) adj. Headaches need to interfere significantly with function or quality of life despite modifica⦠The terms refractory shock and irreversible shock are widely used by physicians and other medical workers to refer to types of shock that present particularly difficult problems. b : unresponsive to stimulus. alteration of refractary, from Latin refractarius, irregular from refragari to oppose, from re- + -fragari (as in suffragari to support with one's vote), Theme music by Joshua Stamper ©2006 New Jerusalem Music/ASCAP. See more. The National Cancer Institute breaks it down even further to say that there are two main types of refractory myeloma patients: 1. Learn more. Refractory and Intractable – The refractory is, when you’re reading the definitions, the one that is the best from medical terms is – resistant to treatment: a refractory case of acne. These example sentences are selected automatically from various online news sources to reflect current usage of the word 'refractory.' [n -RIES] Medical Definition of Refractory. Change your default dictionary to American English. G-POEM has been explored in 2 studies and is targeted for patients with gastroparesis refractory to conventional medical treatment. Please tell us where you read or heard it (including the quote, if possible). 1pertaining to a disorder that is resistant to treatment. Can you spell these 10 commonly misspelled words? Learn more. An example of someone who is refractory is a person who refuses to listen to the rules. conformable, docile, obedient, ruly, submissive, tractable. Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fatigable muscle weakness. Refractarius, like refractory, is the result of a slight variation in spelling. If your doctor thinks you have refractoryepilepsy, he or she may suggest that you visit a medical center thatspecializes in epilepsy. by Debroah Neiss Report definition. 1. hard or impossible to manage; stubbornly disobedient: a refractory child. ungovernable rage intractable suggests stubborn resistance to guidance or control. Symptoms 1. Definition of Refractory. Definition of refractory. They may also have injuriesthat result from their seizures. An example of something refractory is a material like silica or alumina that are difficult to melt. Medical Definition of Refractory anemia Medical Author: William C. Shiel Jr., MD, FACP, FACR Refractory anemia : Anemia that is unresponsive to treatment. 2 a : resistant to treatment or cure a refractory lesion. Looking for definition of Refractory? One of a number of ceramic materials for use in high-temperature structures or equipment. The causes, symptoms, and treatment of refractory epilepsy, which develops when your seizures aren't brought under control by medicine. Mosby's Medical Dictionary, 8th edition. Test Your Knowledge - and learn some interesting things along the way. Refractory. Refractory: In medicine, describes a disease or condition that does not respond to treatment. The criteria include the following: 1. Refractory. Origin: L. Refractorius This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008) Lexicographical Neighbors of Refractory Refractory definition, hard or impossible to manage; stubbornly disobedient: a refractory child. 'Nip it in the butt' or 'Nip it in the bud'? In view of these issues, the term refractory ascites has often generated confusion in the past and made it difficult to compare the results of clinical studies performed by different investigators. The term high temperatures is somewhat indefinite but usually means above about 1830°F (1000°C), or temperatures at which, because of melting or oxidation, the common metals cannot be used. Delivered to your inbox! Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. 2 given to resisting control or discipline by others. First it's important to make sure that the diagnosis of epilepsy is correct and that the proper medicines are being used in the best way for each person. Related Sources. CONTINUE SCROLLING OR CLICK HERE FOR RELATED SLIDESHOW Source: National Institute of Health. Introduction: Refractory Description of Refractory. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. Relapsed and refractory multiple myeloma (MM) constitutes a specific and unmet medical need. Patients with relapsed/refractory disease are defined as those who, having achieved minor resp ⦠The meaning of refractory cancer is cancer that fails to respond to medical treatment. These medical condition or symptom topics may be relevant to medical information for Refractory: unruly children ungovernable implies either an escape from control or guidance or a state of being unsubdued and incapable of controlling oneself or being controlled by others. acts of sabotage by a recalcitrant populace willful implies an obstinate determination to have one's own way. Median survival ranges from as little as 6 to 9 months, and responses to treatment are characteristically short. Define Refractory by Webster's Dictionary, WordNet Lexical Database, Dictionary of Computing, Legal Dictionary, Medical Dictionary, Dream Dictionary. Learn more. Medical Author: William C. Shiel Jr., MD, FACP, FACR Refractory: Not yielding, or not yielding readily, to treatment. Resistant to treatment: a refractory case of acne. a willful disregard for the rights of others headstrong suggests self-will impatient of restraint, advice, or suggestion. believing that rules are only for other people, he's been refractory virtually his entire life. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. People withrefractory epilepsy may have trouble at work or school. 2. This may present as resistance to treatment from the start, or … “Refractory.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/refractory. 'All Intensive Purposes' or 'All Intents and Purposes'? Taking an antidepressant or going to psychological counseling (psychotherapy) eases depression symptoms for most people. This may present as resistance to treatment from the start, or ⦠by Ka Deans Report definition Refractory in Medical Dictionary Not yielding, or otherwise not yielding readily, to treatment. The causes, symptoms, and treatment of refractory epilepsy, which develops when your seizures aren't brought under control by medicine. (Entry 1 of 2) 1 : resisting control or authority : stubborn, unmanageable. Refractory: Related Topics. All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. home / medterms medical dictionary a-z list / anemia, refractory definition Symptoms must be consistent with those defined by the International Classification of Headache Disordersfor migraine or chronic migraine. Refractories definition: unmanageable or obstinate | Meaning, pronunciation, translations and examples See the full definition for refractory in the English Language Learners Dictionary, Thesaurus: All synonyms and antonyms for refractory, Nglish: Translation of refractory for Spanish Speakers. 2. resisting ordinary methods of treatment. They may worry alot about when their next seizure will come. refractory meaning: 1. not affected by a treatment, change, or process: 2. difficult to control; unwilling to obey….
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